Outer membrane permeation of Bacteroides fragilis by cephalosporins.

نویسندگان

  • A Yotsuji
  • J Mitsuyama
  • R Hori
  • T Yasuda
  • I Saikawa
  • M Inoue
  • S Mitsuhashi
چکیده

Outer membrane permeation of Bacteroides fragilis by cephalosporins was examined by a previously described method. The permeation parameters of cephalosporins in B. fragilis were close to 10(-5) cm3/min per microgram of cell dry weight. These values were about an order of magnitude lower than those in Escherichia coli. In B. fragilis, the permeation was not directly proportional to the hydrophilicity of cephalosporins, and the ion selectivity was weak.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 32 7  شماره 

صفحات  -

تاریخ انتشار 1988